Publications

Objective: There is currently a lack of structured and transparent evidence-based processes for developing diagnostic criteria. Using a GRADE-informed approach, we have developed an innovative set of diagnostic criteria for fetal alcohol spectrum disorder (FASD).Study Design and Setting: Our research team developed de novo methods for developing guidance for diagnostic criteria, as part of the review and update of the Australian Guide to Diagnosis of FASD.Results: Using adapted evidence-to-decision frameworks, we were able to include or exclude clinical features in the diagnostic criteria for FASD. Application of GRADE principles to diagnostic criteria provided a systematic and clear process for generating recommendations.

Using updated epidemiological and treatment data, this study sought to provide an updated estimate of the unmet demand for AOD treatment in Australia.

This study examines if prenatal alcohol exposure can affect the flow of blood between the fetus and placenta, which may lead to different changes in the placenta depending on the sex of the fetus.

The purpose of this study was to determine whether subtle changes in facial shape with prenatal alcohol exposure found in 12-month-old children were evident at age 6 to 8 years using extended phenotyping methods and, if so, whether facial characteristics were similar to those seen in fetal alcohol spectrum disorder.

In addiction treatment services in New South Wales, Australia, patients undergo routine health screening on treatment entry and annually thereafter. An integrated pregnancy and contraceptive screening tool was developed. The aim of this cross-sectional study was to report the feasibility and preliminary outcomes of this tool.

This study aims to determine whether alcohol exposure during the periconceptional period induced oxidative stress and reduced mtDNA in maternal liver and the placental labyrinth and junctional zone.